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muTarget
connect mutation status to gene expression changes in solid tumours
Running parameters
Selected gene:
ZC3H12A
Tumor type(s):
Bladder cancer, Breast cancer (TCGA)
Mutation type:
All somatic mutations
Mutation prevalence at least:
2%
Mutation filter:
Off
- exclude patients with mutations in:
-
- include patients with mutations in:
-
P value cutoff:
0.01
Fold change cutoff:
1.44
FDR cutoff:
No FDR filter
Show plot for:
top 5
Gene ontology:
Off
RESULTS
Bladder cancer
Mutation of
Mean expression (mutant)
Mean expression (wild)
Number of mutant
Number of wild
FC (mutant/wild)
Direction
p-value
HECW2
557.17
1445.06
12
396
2.56
down
1.35e-03
SYBU
598.08
1445.96
13
395
2.44
down
2.04e-03
MRC1
789.33
1453.11
21
387
1.85
down
2.23e-03
PALB2
595.77
1446.03
13
395
2.44
down
2.48e-03
KIF23
2981.5
1379.68
10
398
2.16
up
2.66e-03
PCDHB11
2255.23
1391.42
13
395
1.62
up
3.85e-03
ZNF829
557.9
1440.58
10
398
2.56
down
3.90e-03
ARHGAP9
2430.18
1390.92
11
397
1.75
up
4.36e-03
IL1RAPL1
571.8
1440.23
10
398
2.5
down
4.91e-03
ITIH2
629.08
1442.88
12
396
2.27
down
4.93e-03
Download results table for all significant genes
Download plots as pdf
Breast cancer
Mutation of
Mean expression (mutant)
Mean expression (wild)
Number of mutant
Number of wild
FC (mutant/wild)
Direction
p-value
CDH1
674.18
444.63
138
841
1.52
up
8.44e-08
TEX15
758.63
469
27
952
1.62
up
4.42e-05
DNAH8
791.69
467.38
29
950
1.69
up
6.01e-04
MYH9
869.93
465.42
28
951
1.87
up
1.11e-03
CPS1
915.35
467.84
20
959
1.96
up
1.35e-03
TG
287.64
481.95
25
954
1.67
down
1.67e-03
ANKRD12
718
471.19
23
956
1.52
up
4.04e-03
RNF213
750.59
470.69
22
957
1.59
up
4.38e-03
Download results table for all significant genes
Download plots as pdf
